Abstract

A chemical difference between compartments can change how fast they grow without changing how many compartments of each kind there are: in an asynchronously dividing population, accumulated size and offspring number are out of phase. We prove a quantitative finite-batch enrichment theorem for an explicit four-species count reaction network in which every compartment grows by drawing on one shared finite precursor pool while its resident feeds and removal channels remain maintained. Starting from any hh high-state and \ell low-state newborns in explicit, nonempty, chemically certified regions around two stationary compositions, the high-state cell-count odds at the nutrient hitting time exceed esh/e^{s}h/\ell by the deadline TT, except on an event of probability at most Echem(N,M,T)+Esel(N,s)+Etime(N,γ,T)\mathcal E_{\mathrm{chem}}(N,M,T)+\mathcal E_{\mathrm{sel}}(N,s)+\mathcal E_{\mathrm{time}}(N,\gamma,T), with all three terms explicit. At s=0.1s=0.1 and T=8/γT=8/\gamma the error is at most M(32+4/(21γ))ecN+e19N/500000+eN/2500M(32+4/(21\gamma))e^{-cN}+e^{-19N/500000}+e^{-N/2500} with c=1/(1.024×1021)c=1/(1.024\times10^{21}), and a sharper retained bound is OM,γ(Ne3cN)O_{M,\gamma}(Ne^{-3cN}). No fitness parameter is imposed: the growth advantage is the certified difference in resident concentration of the growth species, and chemical fidelity of every descendant is proved rather than assumed. The proof combines a size-position exponential that controls chemical recovery across divisions without any recovery clock, ancestral size totals that survive complementary division unchanged, and a single finite stopped law under which all failure branches are bounded without independence assumptions. For two founders the success event forces a high-state frequency of at least 4/74/7. The finite stopped-law theorem and its quantitative consequences are verified in Lean 4; the identification with an ongoing nonexplosive count process up to the stopping event is a conventional localization argument. The copy numbers for which the bound is informative are astronomically large, and the result is a theorem about a specified effective model, not an experimental calibration.