{
  "inputs": {
    "GPX": {
      "G": 371.56,
      "z0": 1.78,
      "E": 50.0,
      "a": 0.21,
      "b": 0.04,
      "c": 10.0,
      "k": 3.2
    },
    "TRX": {
      "T": 0.505,
      "z0": 0.075,
      "E": 19.096,
      "a": 0.4,
      "b": 0.00072,
      "c": 0.003,
      "d": 15.0,
      "e": 2.1,
      "k": 20.0
    },
    "SOURCE": {
      "P": 30.3,
      "P0": 0.3,
      "K": 57.0,
      "V": 375.0
    },
    "quotas": [
      10.0,
      4.0
    ]
  },
  "configured": {
    "repairable": true,
    "ceilings": [
      10.351641535399606,
      5.143546797661162
    ],
    "carrier_floors": [
      105.42,
      0.21730627145899428
    ],
    "nadph_floors": [
      0.023803129687333436,
      0.9403192156718506
    ],
    "L": 0.9403192156718506,
    "currents": [
      10.348943552053882,
      4.000000000000001
    ],
    "minimum": 0.11371266775153288,
    "quota_only": 0.11094735600193978,
    "overdelivery": [
      0.34894355205388194,
      8.881784197001252e-16
    ],
    "isolated": [
      0.07764044451482575,
      0.031699244571982796
    ]
  },
  "fixed_paper_exact": {
    "XG": "3294375/138400918",
    "XT": "460180/489387",
    "carrier_T": "5000/23009",
    "carrier_G_bracket": [
      "722237/2000",
      "1805593/5000"
    ],
    "scale_bracket": [
      "8887638759786659/78158739404775000",
      "22219103027645887/195396901842300000"
    ],
    "tighter_scale_bracket": [
      "1375295573957003439325612012893683033514433/12094479895257437750242680518751986684475000",
      "114607964496416953277134334407934589860359/1007873324604786479186890043230443272925000"
    ],
    "quota_only": "2958431357/26665181250",
    "redesign_GSH_bracket": [
      361,
      362
    ],
    "redesign_enzyme_upper": "366271/7581",
    "separate_success_joint_failure": true,
    "ceiling_tests": true,
    "opposite_sign_pair": true,
    "evidence": "Fresh rational checks under the paper equations; Lean is not rerun"
  },
  "fixed_parameter_box": {
    "threshold_upper": [
      "1272233597250/21500241900829",
      "30540253570341200/28741682362971499"
    ],
    "target": "3/2",
    "demand_upper": "81271285086677/5182475900450",
    "scale": "11621793767394811/92312851976765625",
    "command_with_5pct_tolerance": "46487175069579244/350788837511709375",
    "scope": "Fixed nominal box: E +/-1%, reductase k +/-5%; sufficient, not optimal"
  },
  "boundary_state": {
    "x": 0.9403192156718506,
    "z": 5.219305297729281,
    "e1": 0.7164506163257354,
    "e2": 0.0028658024653029418,
    "zT": 0.2876937285410058,
    "h": 0.2666666666666667,
    "w": 0.06400000000000002,
    "v": 8.765333333333336,
    "g": 361.11852360207615,
    "e0": 49.28068358120896,
    "y": 0.21730627145899423,
    "r": 9.999999999999998,
    "nadp": 29.35968078432815
  },
  "boundary_residual": 3.552713678800501e-15,
  "source_capacity": 42.64225040682483,
  "boundary_accounting": {
    "NADPH": 14.348943552053882,
    "peroxide": 14.349135552053884,
    "external_Prx_repair": 0.00019200000000000006
  },
  "constant_tolerance_command": 0.11969754500161356,
  "inhibited_source_example": {
    "repairable": true,
    "ceilings": [
      10.351641535399606,
      5.143546797661162
    ],
    "carrier_floors": [
      105.42,
      0.21730627145899428
    ],
    "nadph_floors": [
      0.023803129687333436,
      0.9403192156718506
    ],
    "L": 0.9403192156718506,
    "currents": [
      10.348943552053882,
      4.000000000000001
    ],
    "minimum": 0.1350979090619479,
    "quota_only": 0.1318125421572617,
    "overdelivery": [
      0.34894355205388194,
      8.881784197001252e-16
    ],
    "isolated": [
      0.07801006162877948,
      0.0376607263306462
    ]
  },
  "reference_comparison": {
    "isolated": [
      {
        "x": 8.15223925952398,
        "current": 10.35141133625107
      },
      {
        "x": 20.91957799417111,
        "current": 5.129762886844597
      }
    ],
    "joint_x": 0.3597902880127309,
    "joint_currents": [
      10.344228315375991,
      2.440510390473581
    ]
  },
  "redesign_candidates": [
    {
      "g": 361.3505535873055,
      "E": 48.313663961843275,
      "admissible": true,
      "decision": {
        "repairable": true,
        "ceilings": [
          10.00251744333234,
          5.143546797661162
        ],
        "carrier_floors": [
          361.350553587307,
          0.21730627145899428
        ],
        "nadph_floors": [
          0.940319215672052,
          0.9403192156718506
        ],
        "L": 0.940319215672052,
        "currents": [
          9.999999999999998,
          4.000000000000266
        ],
        "minimum": 0.11094735600194239,
        "quota_only": 0.1109473560019403,
        "overdelivery": [
          -1.7763568394002505e-15,
          2.6556534749033744e-13
        ],
        "isolated": [
          0.07924811142995736,
          0.031699244571982796
        ]
      },
      "full_residual": 1.7763568394002505e-15
    },
    {
      "g": 0.0027673957880305034,
      "E": 90746.60799803272,
      "admissible": true,
      "decision": {
        "repairable": true,
        "ceilings": [
          2951.159794391434,
          5.143546797661162
        ],
        "carrier_floors": [
          0.0027673957880305043,
          0.21730627145899428
        ],
        "nadph_floors": [
          0.9403192156718319,
          0.9403192156718506
        ],
        "L": 0.9403192156718506,
        "currents": [
          10.000000000000204,
          4.000000000000001
        ],
        "minimum": 0.11094735600194142,
        "quota_only": 0.11094735600193978,
        "overdelivery": [
          2.042810365310288e-13,
          8.881784197001252e-16
        ],
        "isolated": [
          0.07924811142995696,
          0.031699244571982796
        ]
      },
      "full_residual": 1.1874234928654914e-10
    }
  ],
  "numerical_dynamics": [
    {
      "setting": "reference",
      "scale": 0.1,
      "perturbation": "carrier oxidation",
      "largest_eigen_real": -0.0029999342839263326,
      "sampled_service_min": [
        10.343415626301873,
        1.9032054335490327
      ],
      "sampled_domain_min": 0.0029552586724342273,
      "final_distance": 1.1726220019298017e-07,
      "equilibrium_residual": 2.6645352591003757e-15
    },
    {
      "setting": "reference",
      "scale": 0.1,
      "perturbation": "enzyme allocation",
      "largest_eigen_real": -0.0029999342839263326,
      "sampled_service_min": [
        10.302228315375991,
        2.4104727270917863
      ],
      "sampled_domain_min": 0.0029552586724342273,
      "final_distance": 2.2642914737636133e-08,
      "equilibrium_residual": 2.6645352591003757e-15
    },
    {
      "setting": "boundary",
      "scale": 0.11371266775153288,
      "perturbation": "carrier oxidation",
      "largest_eigen_real": -0.0030012069650584487,
      "sampled_service_min": [
        10.348294954415886,
        3.631855999999999
      ],
      "sampled_domain_min": 0.0028658024653029418,
      "final_distance": 9.988771200453161e-08,
      "equilibrium_residual": 1.7763568394002505e-15
    },
    {
      "setting": "boundary",
      "scale": 0.11371266775153288,
      "perturbation": "enzyme allocation",
      "largest_eigen_real": -0.0030012069650584487,
      "sampled_service_min": [
        10.306943552053882,
        3.944230385643005
      ],
      "sampled_domain_min": 0.0028658024653029418,
      "final_distance": 1.872562553628665e-08,
      "equilibrium_residual": 1.7763568394002505e-15
    },
    {
      "setting": "slack",
      "scale": 0.12,
      "perturbation": "carrier oxidation",
      "largest_eigen_real": -0.003004279758761918,
      "sampled_service_min": [
        10.349640346637148,
        4.231028209491655
      ],
      "sampled_domain_min": 0.0028426323544573744,
      "final_distance": 6.947441492932693e-08,
      "equilibrium_residual": 3.552713678800501e-15
    },
    {
      "setting": "slack",
      "scale": 0.12,
      "perturbation": "enzyme allocation",
      "largest_eigen_real": -0.003004279758761918,
      "sampled_service_min": [
        10.308164848596553,
        4.497447262020977
      ],
      "sampled_domain_min": 0.0028426323544573744,
      "final_distance": 1.164088331284674e-08,
      "equilibrium_residual": 3.552713678800501e-15
    }
  ],
  "orthant_obstruction_pair": [
    -0.18134197534697058,
    14.444740944083048
  ],
  "nonmonotone_dimensionless": {
    "success_scale_interval": [
      0.4651530771650466,
      1.9348469228349532
    ],
    "unique_equilibrium": true,
    "explanation": "h derivative = ((1-x)^2+1/5)/(1-x)^2 >0; more source eventually breaks the quota"
  }
}